Nucleus Genomics vs Genomisaur
Nucleus Genomics bundles whole genome sequencing with 20+ polygenic scores and hundreds of conditions for $399 plus an annual membership. Genomisaur runs 71 polygenic risk scores against a supported array file or WGS VCF from any provider for $29.99 one-time, plus $20 for WGS processing. Here's how they actually compare.
At a glance
You already have a supported raw DNA file or a WGS VCF from any provider and want 71 informational polygenic risk scores without a new kit or subscription.
You do not have any DNA data yet, want true 30× whole genome sequencing you can re-analyze forever, and are fine with a ~6-week turnaround and a recurring membership.
Pricing
Public list prices. Genomisaur Health Reports are $20–$29.99 one-time.
| Option | Price | What it is |
|---|---|---|
| Genomisaur — Full Health Report | $29.99 one-time | 71 PRS + trait predictions from existing DNA data |
| Nucleus Genomics | $399 kit + $39/yr | 30× WGS + ~20 PRS + 800+ conditions + traits |
| Turnaround | ~20 minutes | ~6 weeks (lab sequencing) |
| Ongoing cost | $0 (optional $20/yr auto-update) | $39/yr membership to keep viewing reports |
Competitor prices are public list prices from each vendor's site as of 2026 and change often; confirm on the vendor's site before purchasing.
Feature comparison
Side-by-side on the things that actually change what the product does for you.
| Feature | Genomisaur | Nucleus Genomics | Edge |
|---|---|---|---|
| Requires a new kit? | No — bring existing DNA data | Yes — saliva kit + WGS | |
| Accepts 23andMe / AncestryDNA / MyHeritage | Yes | No — WGS only | |
| Accepts WGS VCF from any provider | Yes — every health tier | Compatible VCFs or Nucleus sequencing | |
| Polygenic risk scores included | 71 PRS across 14 categories | ~20 PRS at launch, growing | |
| Trait and lifestyle predictions | Yes — appearance + lifestyle | Yes | |
| Per-score source publications | Every score card links to its GWAS | Limited methodology disclosure | |
| Turnaround | ~20 minutes | ~6 weeks | |
| Recurring fees | None (optional $20/yr updates) | $39/yr membership |
What each one does well
Genomisaur
- $29.99 one-time vs $399 + $39/yr — no subscription treadmill
- Works with supported array files or a WGS VCF from any provider
- 71 peer-reviewed PRS across 14 categories with per-score performance metrics
- ~20 minute turnaround instead of ~6 weeks
- Your report is yours — download PDF, delete your data, no lock-in
Nucleus Genomics
- Whole genome sequencing is included — useful if you have no DNA data yet
- Hundreds of single-gene conditions on top of PRS
- Polished consumer app with a longevity-focused frame
If you already have consumer DNA data (roughly 20 million Americans do), Genomisaur is the faster and cheaper path to polygenic risk scores — 71 of them for $29.99, no subscription. If you have no DNA data and specifically want WGS in the box, Nucleus Genomics is a more complete one-stop purchase at $399 + $39/yr.
Frequently asked questions
Does Nucleus accept 23andMe or AncestryDNA uploads?
No. As of 2026, Nucleus Genomics only works with their own WGS data or compatible VCF uploads. If your existing data is a 23andMe or AncestryDNA genotype file, Genomisaur is the direct path to a PRS report from it.
How much does Nucleus Genomics actually cost over time?
$399 for the kit plus $39 per year to keep viewing and re-running reports. Over 3 years that is 477 USD. Genomisaur's Full Health Report is $29.99 one-time; optional auto-update subscription is $20/yr.
Does Genomisaur replace whole genome sequencing?
Genomisaur does not perform sequencing. It analyzes a WGS VCF you already have from any provider, or a supported consumer-array file, for polygenic risk and traits. It is not a substitute for clinical WGS interpretation.
Is any of this a replacement for medical advice?
No. Both Nucleus and Genomisaur deliver informational consumer reports and should be discussed with a qualified healthcare provider before making medical decisions.
Informational, not diagnostic
Consumer genetic reports — ours, Nucleus Genomics's, and others — are informational. Carrier and polygenic risk results should be discussed with a qualified healthcare provider or genetic counselor before making medical or reproductive decisions.